CEO

CVs for CEO + President (below)

David W. Smith, M.D.
Founder & CEO

Visiting Scientist Chicago North Shore University
Department of Neurosurgery

Former Consultant to
Human Performance Laboratory Cincinnati
Children's Hospital and Medical Center

Phone | 765 969 6921
eMail | DavDoc1960@gmail.com

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• Biography

David W. Smith MD, ACP, BS (Chemistry), Board Certified (Internal Medicine Specialist) with recognition as a visiting scientist for both The Human Performance Laboratory for the Division of Sports Medicine at Cincinnati Children's Hospital Medical Center and for the North Shores Division of Neurosurgery and North Shore Neurological Institute, Chicago Illinois. Over his 30-year medical career he has served as Chief of Medicine at Reid Hospital and Healthcare Services, and has founded both Xennovate Medical LLC and TBI Innovations LLC (both established to further Dr. Smith’s inventions, discoveries and intellectual property). As Chief Science officer, he has served as lead design and medical education consultant to GlaxoSmithKline (GSK is $90B+ Pharmaceutical and Healthcare company), GENTEX Corp (largest manufacturer of USAF helmets), and Materials Modification Inc. (nanomaterials and coating pioneer to the military complex). Consistent with his Internal Medicine background and experiences Dr. Smith has Intellectual Property and peer-reviewed publications in many diverse fields of science, giving him a unique perspective in already overcoming a broad spectrum of significant medical paradigms. Specifically, his firm background in analytical chemistry (with an added emphasis in physics), affixed to his medical degree and internal medical career, have allowed him to bring a better understanding of energy interactions and impartations to the human body (particularly useful in Traumatic Brain Injury).

Dr. Smith discovered and then pioneered “SLOSH Theory,” which is the basis of his compression collar invention for humans designed specifically to mitigate SLOSH energy absorption, thereby seeking to reduce the risk of brain damage from traumatic events. Further, he recently co-authored (with Julian Bailes MD, a world-renowned neurosurgeon) a presentation on “The Physics of Traumatic Brain Injury-Revisited,” Congress of Neurological Surgeons, Annual Meeting, San Diego, CA, Sept 2016. This venue represents the largest gathering of Neurosurgeons and Brain Injury Specialists in the world, and that event provided the backdrop for Dr. Smith’s disclosure of his latest thinking on how “cavitation” can explain how the physics of a concussive wave can produce the chemistry of a TBI. In his scientific role with Xennovate Medical, he has also presented several novel battlefield dressings to the Department of the Army Research Lab (DARPA) at the Aberdeen Proving Grounds, Aberdeen, MD.

Dr. Smith has assisted Gentex Corp in successfully being awarded a $90M contract in the arena of mitigating the forces involved in human ejections from supersonic aircraft. He was the lead scientist in Xennovate’s two-year funding effort with DARPA’s Joint Improvised Explosive Device Defeat Organization (JEIDDO).

• Education & Certifications

• Patent Information

DEVICE TO REDUCE SLOSH ENERGY ABSORPTION AND ITS DAMAGING EFFECTS THROUGH REDUCING THE FLOW OF ONE OR MORE OUTFLOW VESSELS OF THE CRANIUM BY COMPRESSING SAID VESSELS. APP# 12/931,415, PUBLICATION NUMBER: US 2012/0197290 A1

Methods and Devices to reduce damaging effects of concussive forces or blasts on a subject, App# 13/489,536

METHOD TO REDUCE SLOSH ENERGY ABSORPTION AND ITS DAMAGING EFFECTS THROUGH THE REDUCTION OF INELASTIC COLLISIONS IN AN ORGANISM, APP# 20110065637

Devices and Systems to Mitigate Traumatic Brain and Other Injuries Caused by Concussive or Blast Forces | US20140343599A1

Methods and Devices to Reduce the Likelihood of Injury from Concussive or Blast Forces | US20160157870A1

Method to reduce SLOSH energy absorption and its damaging effects through the reduction of inelastic collisions in an organism | US20189987020

Device to Reduce SLOSH Energy Absorption and its Damaging Effects Through the Reduction of the Flow of One or More Outflow Vessels of the Cranium | US20160008004A1

Methods and Devices to Reduce Damaging Effects of Concussive or Blast Forces on a Subject | US20160317159A1

Method to reduce SLOSH energy absorption and its damaging effects through the reduction of inelastic collisions in an organism | US8985120B2

Methods and devices to reduce the likelihood of injury from concussive or blast forces | US20148900169

ADHESIVE ATTACHMENT AND REMOVAL DEVICE US 7,309,809 B2

SELF-CLEANSING BLADDER DRAINAGE CATHETER US 2008/0172040 A1

METHOD OF IMPARTING A FLEXURAL MODULUS TO MATERIALS, AND PRODUCTS RESULTING THEREFROM US20080058858

NASAL DILATOR DESIGN PATENT WITH GLAXO SMITH KLINE US D662,203S

• Publications

Red Blood Cell Response to Blast Levels of Force Impartations Into Freely Moveable Fluid Surfaces Inside a Closed Container | Frontiers in Physics | 21 August 2018 | Smith, et al.

Cranial Venous Blood Cavitation: A Possible Mechanism of Traumatic Brain Injury Associated with Blast Wave exposure and Head Impacts | Military Medicine | September 2017.

A jugular vein compression collar prevents alterations of endogenous electrocortical dynamics following blast exposure during special weapons and tactical (SWAT) breacher training.

Mild jugular compression collar ameliorated changes in brain activation of working memory after one soccer season in female high school athletes | Journal of Neurotrauma | 2017.

Neck collar with mild jugular vein compression ameliorates brain activation changes during a working memory task after a season of high school football, Journal of Neurotrauma · February 2017 DOI: 10.1089/neu.2016.4834

Internal Jugular Vein Compression: A Novel Approach to Mitigate Blast Induced Hearing Injury, Otology & Neurotology: · January 2017

Effect of Internal Jugular Vein Compression on Intracranial Hemorrhage in a Porcine Controlled Cortical Impact Model, Journal of Neurotrauma 34(8) · August 2016, DOI: 10.1089/neu.2016.4648

Analysis of head impact exposure and brain microstructure response in a season-long application of a jugular vein compression collar: A prospective, neuroimaging investigation in American football, British Journal of Sports Medicine 50(20): bjsports-2016-096134 · June 2016, DOI: 10.1136/bjsports-2016- 096134

The Effects of External Jugular Compression Applied during Head Impact Exposure on Longitudinal Changes in Brain Neuroanatomical and Neurophysiological Biomarkers: A Preliminary Investigation, Frontiers in Neurology 7(24) · June 2016, DOI: 10.3389/fneur.2016.00074

LETTERS TO THE EDITOR-IN-CHIEF RESPONSE, Journal of Orthopaedic and Sports Physical Therapy 44(6):459-460 · June 2014

Altitude Does Not Reduce Concussion Incidence: Response, The Orthopaedic Journal of Sports Medicine 2(3) · March 2014, DOI: 10.1177/2325967114527235

Rates of Concussion Are Lower in National Football League Games Played at Higher Altitudes, January 2014, DOI: 10.2519/jospt.2014.5298

Altitude Modulates Concussion Incidence: Implications for Optimizing Brain Compliance to Prevent Brain Injury in Athletes, The Orthopedic Journal of
Sports Medicine 1(6) · November 2013, DOI: 10.1177/2325967113511588

Effect of slosh mitigation on histologic markers of traumatic brain injury Laboratory investigation, Journal of Neurosurgery 117(6):1110-1118 · December
2012, DOI: 10.3171/2012.8. JNS12358

Internal Jugular Vein Compression Mitigates Traumatic Axonal Injury in a Rat Model by Reducing the Intracranial Slosh Effect, Neurosurgery 70(3):740- 6 · September 2011, DOI: 10.1227/NEU.0b013e318235b991

The Impact of Blast Exposure and the Ameliorating Effect of a Collar Device: An fMRI study | The 24th Annual Meeting of the Organization for Human Brain Mapping, Singapore, June 17-21, 2018 | Yuan W, Barber Foss KD, Thomas S, Galloway R, DiCesare C, Dudley J, Leach J, Scheifele P, Smith D, Altaye M., Rhea CK, Thomas Talavage, Myer GD.

President

Neil M. Kosterman
Co-Founder & President
Entrepreneur & Turnaround Business Expert
General Management, Marketing, Sales, & Business Development
Phone | 608 305 8799
eMail | NeilKo@mac.com

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• Biography

Co-Founder of TBI Innovations to develop and commercialize innovative technology discovered by David W. Smith, M.D., CEO of TBII. The technology, named SLOSH Theory, led to a license agreement now incorporating numerous patents, which protect inventions derived from SLOSH Theory. Referred to internally as the Q-collar™, the first and highly prominent invention for protection from brain damage due to shock-trauma to the head (often called concussions) has been launched in Canada while our licensee works with the USFDA to coordinate the pivotal study anticipating market launch in 2019.

Mr. Kosterman has been starting new companies and working as an independent turnaround specialist for troubled assets since 1992. He has been involved in over a dozen startup and turnaround situations, including three as a principal. His most recent turnaround assignment, as President, was for a publicly traded medical company, where he stopped losses and put the company back on a profitable track in two quarters.

He was a Vice President for significant operations of Pfizer, CR Bard, and Smith & Nephew. In his corporate career he variously held positions in sales, marketing, product development, and general management, as well as strategist, especially related to acquisitions, and the Wall Street contact for the US subsidiary of a UK company.

He started new divisions within corporate America (Intrepreneur) and had several major successes in growing sales and profits through both new product programs and rehabilitating mature products and businesses with a new look and feel. As a consultant, Mr. Kosterman has been involved beyond medical and pharmaceutical products, as well. He has developed specialized training programs and delivered same throughout his career.

Mr. Kosterman’s marketing and business development successes have typically occurred through closely integrating them with the development of new or improved products. At Pfizer, Mr. Kosterman was the architect of an innovative database-marketing program (22% response rate with 76% retention) used successfully with colostomy product users in their homes. Mr. Kosterman graduated from the University of Wisconsin-Madison in with a degree in Finance, Investments and Banking.

• Education & Certifications

BBA | University of Wisconsin-Madison | Finance, Investments and Banking | 1965-1972

A Rhatigan Design Award for a product catalog

Two separate awards from American Corporate Identity

Numerous workshops and training programs delivered for sales and management attendees

Architect of various systems for management and control with particular emphasis on FDA and ISO processes for product development, manufacturing, and regulatory management and control.

• Experience

2011 - Present

TBI Innovations LLC | Indiana | Co-Founder | Board Member | President

Founded to develop & commercialize Inventor Smith technologies

2005 - 2016

Xennovate Medical LLC | Indiana | Managing Director (COO)

Worked with Dr. Smith to develop & commercialize clever new hydrocolloid products | Negotiated contracts with major US corporations

1990 - Present

DeltaQuest Consulting | Madison WI | President

2003

Xechem International Inc. (NASDAQ: XKEM) | New Jersey | Board Member

2001

WRP Corporation (NASDAQ: WRPC) | Chicago | President

Stopped losses in two quarters and put on path for rapid, profitable growth

1991 - 1999

Various entrepreneurial programs, plus licensing consultant to WARF

1988 - 1990

Smith & Nephew Inc. | Chicago | Vice President, Corporate Development

1989 - 1990

SoloPak Pharmaceuticals Inc. | Chicago | Vice President

1988

Smith & Nephew United Inc. | Florida | President

1983 - 1988

Pfizer United Division | Florida | Vice President Marketing & Sales

1980 - 1983

Bard Urological Specialties Division of CR Bard | New Jersey | President

1970 - 1980

Ohio Medical Products | Madison | General Manager

Started as accountant | two sales territories | three production manager positions, ending as General Manager for Field Engineering

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